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Article

Scale-up and optimization of the low-temperature inducible cspA promoter system.

Biotechnology progress - 1 Jan 2000

Vasina J A, Peterson M S, Baneyx F

Abstract excerpt

The performance of the major Escherichia coli cold-shock promoter in directing the synthesis of recombinant proteins at low temperatures was investigated in batch fermentations using a plasmid-encoded transcriptional gene fusion between the cspA promoter region and the lacZ gene. Rapid synthesis of beta-galactosidase was observed when the fermentation broth was chilled to 15 degreesC using a variety of cooling...

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Identifiers

PMID: 9758660
DOI: 10.1021/bp980061p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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