Article
Complete growth inhibition of Escherichia coli by ribosome trapping with truncated cspA mRNA at low temperature.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 1996
Jiang W, Fang L, Inouye M
Abstract excerpt
BACKGROUND: CspA, the major cold-shock protein of Escherichia coli, is transiently induced upon temperature downshift and considered to play an important role in low-temperature adaptation. RESULTS: Overproduction of truncated cspA mRNAs retaining translational ability was found to completely block cell growth at low temperatures. This effect was termed 'low-temperature antibiotic effect of truncated cspA...
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