Article
Enhanced neurotransmitter release is associated with reduction of neuronal branching in a Drosophila mutant overexpressing frequenin.
The European journal of neuroscience - 1 Feb 1998
Angaut-Petit D, Toth P, Rogero O, Faille L, Tejedor F J, Ferrús A
Abstract excerpt
Frequenin is a Drosophila Ca2+ binding protein whose overexpression causes a chronic facilitation of transmitter release at the larval neuromuscular junction and multiple firing of action potentials. These functional abnormalities are similar to those found in other hyperexcitable mutants (Shaker...
Topics
- Animals
- Blotting, Western
- Calcium-Binding Proteins
- Cell Size
- Drosophila Proteins
- Drosophila melanogaster
- Electrophoresis, Polyacrylamide Gel
- Immunohistochemistry
- Larva
- Microscopy, Confocal
- Mutation