Article
Genetic and physiological characterization of a formate-dependent 5'-phosphoribosyl-1-glycinamide transformylase activity in Bacillus subtilis.
Molecular & general genetics : MGG - 1 Feb 1994
Saxild H H, Jacobsen J H, Nygaard P
Abstract excerpt
We have found that Bacillus subtilis possesses a second 5'-phosphoribosyl-1-glycinamide (GAR) transformylase catalysing the first one-carbon transfer reaction in the purine biosynthetic pathway. Inactivation of the purN gene encoding the N10-formyl tetrahydrofolate-dependent enzyme did not result...
Topics
- Acyltransferases
- Bacillus subtilis
- Cloning, Molecular
- Formates
- Genes, Bacterial
- Hydroxymethyl and Formyl Transferases
- Mutation
- Phosphoribosylglycinamide Formyltransferase
- Transformation, Genetic