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hsp72, a Host Determinant of Measles Virus Neurovirulence

28 Oct 2006

Abstract excerpt

Transient hyperthermia such as that experienced during febrile episodes increases expression of the major inducible 70-kDa heat shock protein (hsp72). Despite the relevance of febrile episodes to viral pathogenesis and the multiple in vitro roles of heat shock proteins in viral replication and gene expression, the in vivo significance of virus-heat shock protein interactions is unknown. The present work...

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PMID: 16971451
DOI: 10.1128/jvi.01438-06

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