Article
[Molecular cancer disposition diagnosis exemplified by colorectal carcinoma. What is the contribution of pathology?].
Der Pathologe - 1 Jul 1998
Rüschoff J, Dietmaier W, Bocker T, Wallinger S, Kullmann F, Beham A, Hofstädter F
Abstract excerpt
During the last few years, the molecular basis of several cancer predisposition syndromes has been discovered which offers new tools for cancer prevention and early detection. This will be demonstrated in one of the most frequent hereditary cancer syndromes, namely the hereditary nonpolyposis colorectal cancer (HNPCC) which accounts for about 5% to 8% of CRC. Thereby, families with exclusively CRC (Lynch type I...
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