Article
[Identification of penicillin-resistant Streptococcus pneumoniae in nasopharynx of patient with acute otitis media by PCR].
Nihon Jibiinkoka Gakkai kaiho - 1 Jul 1998
Hotomi M, Ubukata K, Konno M, Samukawa T, Shimada J, Suzumoto M, Yamanaka N
Abstract excerpt
Streptococcus Pneumoniae is a leading cause of acute otitis media (AOM). For most AOM caused by S. pneumoniae, penicillin is the antibiotic of choice. However, there are some recent reports of clinical resistance to penicillin by S. pneumoniae. The sequences of penicillin binding protein, pbpla, pbp2b and pbp2x, genes of penicillin-resistant S. pneumoniae (PRSP) were more highly divergent than those of...
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