Article
Association between MICA gene A4 allele and acute anterior uveitis in white patients with and without HLA-B27.
American journal of ophthalmology - 1 Sept 1998
Goto K, Ota M, Maksymowych W P, Mizuki N, Yabuki K, Katsuyama Y, Kimura M, Inoko H, Ohno S
Abstract excerpt
PURPOSE: Acute anterior uveitis is strongly associated with the HLA-B27 antigen and triggered by the involvement of some external factors. However, it is uncertain whether HLA-B27 itself or other gene(s) near the HLA-B region in a linkage disequilibrium with HLA-B27 predispose to this uveitis. We therefore investigated microsatellite polymorphism in the transmembrane region of the major histocompatibility complex...
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