Article
The Phenotype of Monocytes in Anterior Uveitis Depends on the HLA-B27 Status.
Frontiers in immunology - 1 Jan 2018
Kasper Maren, Walscheid Karoline, Laffer Björn, Bauer Dirk, Busch Martin, Wildschütz Lena, Wang Bo, Loser Karin, Vogl Thomas, Grajewski Rafael S, Langmann Thomas, Heiligenhaus Arnd
Abstract excerpt
HLA-B27 is the allele most frequently associated with human anterior uveitis. The majority of HLA-B27-positive [acute anterior uveitis (AAU)] patients develop clinically distinct symptoms with acute symptomatic onset of flare and a recurrent disease course characterized by a massive cellular ocular infiltrate during uveitis relapse. By contrast, uveitis in HLA-B27-negative [idiopathic anterior uveitis (IAU)]...
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