Article
MICA gene polymorphisms and HLA-B27 subtypes in Japanese patients with HLA-B27-associated acute anterior uveitis.
Investigative ophthalmology & visual science - 1 Mar 1998
Goto K, Ota M, Ando H, Mizuki N, Nakamura S, Inoue K, Yabuki K, Kotake S, Katsuyama Y, Kimura M, Inoko H, Ohno S
Abstract excerpt
PURPOSE: HLA-B27-associated acute anterior uveitis (HLA-B27 AAU) seems to be triggered by external factors in persons with a particular genetic background. It is still uncertain whether HLA-B27 or other gene(s) near the HLA-B region predisposes to uveitis in a linkage disequilibrium with B27. The...
Topics
- Acute Disease
- Adult
- Alleles
- DNA Primers
- DNA, Satellite
- Electrophoresis, Agar Gel
- Female
- Gene Frequency
- Genotype
- HLA-B27 Antigen
- Histocompatibility Antigens Class I
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Uveitis, Anterior