Article
Brittle asthma.
Thorax - 1 Apr 1998
Ayres J G, Miles J F, Barnes P J
Abstract excerpt
We believe that the asthma phenotypes we have defined as types 1 and 2 brittle asthma appear to be defined subgroups of asthma. For example, we have characterised patients with type 1 brittle asthma, as defined in this review, on the basis of peak flow variability and treatment and these patients remain a separate group when assessed by other means such as psychosocial factors, immunoglobulin levels, and atopy....
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