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Article

Soluble Fas mRNA is dominantly expressed in cases with silicosis

14 Jun 1998

Abstract excerpt

Although it is well known that cases with silicosis exhibit various immunological abnormalities, the mechanisms involved in the occurrence of immuno-dysfunction or dysregulation induced by silica compounds have not yet been determined. Fas is a well-known cell surface molecule that is involved in the apoptosis pathway that belongs to the tumour necrosis factor-receptor family. Soluble Fas (sFas) is produced as an...

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PMID: 9741350
DOI: 10.1046/j.1365-2567.1998.00509.x

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