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Evaluation of apoptosis-related gene Fas (CD95) and FasL (CD178) polymorphisms in Iranian rheumatoid arthritis patients.

Rheumatology international - 1 Sept 2012

Mohammadzadeh Adel, Pourfathollah Ali Akbar, Tahoori Mohammad Taher, Daneshmandi Saeed, Langroudi Ladan, Akhlaghi Masoumeh

Abstract excerpt

Apoptosis signals are essential for establishing homeostasis and adequate immune response. Dysregulation of apoptosis-related genes in the immune system, which could be due to gene polymorphisms, conduct to autoimmune diseases including rheumatoid arthritis. In the current study, the apoptosis-related gene Fas_-670A>G, FasL_844C>T, and FasLIVS2nt_124A>G polymorphisms were genotyped in 120 Iranian patients with...

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Apoptosis
Arthritis, Rheumatoid
Case-Control Studies
Fas Ligand Protein
fas Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21879377
DOI: 10.1007/s00296-011-2065-x

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