Article
Inhibitor-resistant OXY-2-derived beta-lactamase produced by Klebsiella oxytoca.
Antimicrobial agents and chemotherapy - 1 Sept 1998
Sirot D, Labia R, Pouedras P, Chanal-Claris C, Cerceau C, Sirot J
Abstract excerpt
Klebsiella oxytoca strains are generally moderately resistant to amoxicillin and ticarcillin due to the activities of the chromosomally encoded OXY-1 and OXY-2 class A beta-lactamase families. These enzymes have the ability to hydrolyze not only penicillins but also cephalosporins, including cefuroxime, ceftriaxone, and aztreonam, and are inhibited by clavulanic acid. A Klebsiella oxytoca strain was isolated from...
Topics
- Drug Resistance, Microbial
- Isoelectric Focusing
- Klebsiella
- Phenotype
- beta-Lactamase Inhibitors
- beta-Lactamases
