Article
Evaluation of Phenotypic Tests to Detect Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella oxytoca Complex Strains.
Journal of clinical microbiology - 20 Apr 2023
Campos-Madueno Edgar I, Moser Aline I, Keller Peter M, Perreten Vincent, Poirel Laurent, Nordmann Patrice, Endimiani Andrea
Abstract excerpt
Klebsiella oxytoca complex (KoC) species may overproduce their chromosomal class A OXY β-lactamases, conferring reduced susceptibility to piperacillin-tazobactam, expanded-spectrum cephalosporins and aztreonam. Moreover, since clavulanate maintains its ability to inhibit these enzymes, the resulting resistance phenotype may falsely resemble the production of acquired extended-spectrum β-lactamases (ESBLs). In...
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