A missense mutation, Val62Ala, in the glucokinase gene in a Norwegian family with maturity-onset diabetes of the young.

doi:10.1080/080352598750013626

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Article

A missense mutation, Val62Ala, in the glucokinase gene in a Norwegian family with maturity-onset diabetes of the young.

Acta paediatrica (Oslo, Norway : 1992) - 1 Aug 1998

Njølstad P R, Cockburn B N, Bell G I, Søvik O

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a form of diabetes mellitus characterized by autosomal dominant inheritance, onset usually before 25 y of age and a primary defect in glucose-stimulated insulin secretion. It is a heterogeneous disorder both with respect to aetiology and clinical fea...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Child
Child, Preschool
Codon
Diabetes Mellitus, Type 2
Female
Glucokinase
Humans
Hyperglycemia
Male
Middle Aged
Mutation, Missense
Norway
Pedigree
Polymerase Chain Reaction

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