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Article

Evolved variants of the membrane protein can partially replace the envelope protein in murine coronavirus assembly.

Journal of virology - 1 Dec 2010

Kuo Lili, Masters Paul S

Abstract excerpt

The coronavirus small envelope (E) protein plays a crucial, but poorly defined, role in the assembly of virions. To investigate E protein function, we previously generated E gene point mutants of mouse hepatitis virus (MHV) that were defective in growth and assembled virions with anomalous morphologies. We subsequently constructed an E gene deletion (ΔE) mutant that was only minimally viable. The ΔE virus formed...

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Identifiers

PMID: 20926558
DOI: 10.1128/JVI.01850-10
PMCID: PMC3004328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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