Article
Identification of a novel ankyrin isoform (AnkG190) in kidney and lung that associates with the plasma membrane and binds alpha-Na, K-ATPase.
The Journal of biological chemistry - 11 Sept 1998
Thevananther S, Kolli A H, Devarajan P
Abstract excerpt
Ankyrins are a family of adapter molecules that mediate linkages between integral membrane and cytoskeletal proteins. Such interactions are crucial to the polarized distribution of membrane proteins in transporting epithelia. We have cloned and characterized a novel 190-kDa member of this family...
Topics
- Amino Acid Sequence
- Animals
- Ankyrins
- Base Sequence
- COS Cells
- Cell Line
- Conserved Sequence
- Dogs
- Genetic Variation
- Humans
- Kidney
- Kidney Medulla
- Kidney Tubules, Collecting
- Lung
- Molecular Sequence Data
- Polymerase Chain Reaction
- Rats
- Sodium-Potassium-Exchanging ATPase