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Article

Bronchial responsiveness and angiotensin-converting enzyme gene polymorphism in sarcoidosis patients.

Chest - 1 Aug 1998

Niimi T, Tomita H, Sato S, Mori T, Kawaguchi H, Sugiura Y, Matsuda R

Abstract excerpt

BACKGROUND: Angiotensin-converting enzyme (ACE) inactivates bradykinin and tachykinins, which are potent bronchoconstrictors and mediators of inflammatory reactions. It has recently been shown that an insertion (I)/deletion (D) polymorphism in the ACE gene accounts for variation in serum ACE level. We investigated bronchial responsiveness in patients with sarcoidosis to determine whether it might be associated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9726736
DOI: 10.1378/chest.114.2.495

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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