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Article

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

1 Sept 1998

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Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 9724636
DOI: 10.1093/emboj/17.17.5001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2PMID 9724636Read ↗

Mdm2 overexpression and p14ARF inactivation are two mutually exclusive events in primary human lung tumorsSemantic proximity Read ↗

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.Semantic proximity Read ↗

Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblastsSemantic proximity Read ↗

Dual Role of the Alternative Reading Frame ARF Protein in CancerSemantic proximity Read ↗

Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylationSemantic proximity Read ↗

P14ARF: The Absence that Makes the Difference.Semantic proximity Read ↗

Stability of nucleolar versus non-nucleolar forms of human p14ARFSemantic proximity Read ↗

MDM2-Mediated Degradation of p14ARF: A Novel Mechanism to Control ARF Levels in Cancer CellsSemantic proximity Read ↗

Human p14ARF-mediated cell cycle arrest strictly depends on intact p53 signaling pathwaysSemantic proximity Read ↗

Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage ResponseSemantic proximity Read ↗

Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cellsSemantic proximity Read ↗

p53 and E2f: partners in life and death.Semantic proximity Read ↗

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