Hemochromatosis: a genetic defect in iron metabolism.

doi:10.1002/(SICI)1521-1878(199807)20:7<562::AID-BIES7>3.0.CO;2-M

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Article

Hemochromatosis: a genetic defect in iron metabolism.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jul 1998

Jazwinska E C

Abstract excerpt

Hemochromatosis (HC), the common inherited disorder in iron metabolism, affects at least 1 in 300 Caucasians. The disorder causes inappropriately high iron absorption and accumulation of excess iron in the parenchymal cells of the major organs of the body. The gene responsible for HC has recently...

Topics

Animals
Chromosome Mapping
Chromosomes, Human, Pair 6
Genetics, Population
HLA Antigens
Hemochromatosis
Hemochromatosis Protein
Histocompatibility Antigens Class I
Humans
Iron
Membrane Proteins
Mice
Mice, Knockout
Mutation
beta 2-Microglobulin

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