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Article

Pathogenesis of hereditary hemochromatosis: genetics and beyond.

Seminars in gastrointestinal disease - 1 Apr 2002

Britton Robert S, Fleming Robert E, Parkkila Seppo, Waheed Abdul, Sly William S, Bacon Bruce R

Abstract excerpt

Hereditary hemochromatosis (HH) comprises several inherited disorders of iron homeostasis characterized by increased gastrointestinal iron absorption and secondary tissue iron deposition. The most common form of this disorder is called HFE-related HH and is caused by homozygosity for the C282Y mutation in the HFE gene. Recently, other less common hereditary forms of iron overload have been recognized and are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12064862

Genes

HFE

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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