Article
Variants of the type II 3beta-hydroxysteroid dehydrogenase gene in children with premature pubic hair and hyperandrogenic adolescents.
Molecular genetics and metabolism - 1 Jul 1998
Nayak S, Lee P A, Witchel S F
Abstract excerpt
To ascertain the potential role of heterozygosity for 3beta-hydroxysteroid (3beta-HSD) deficiency in children with premature pubic hair and adolescent girls with hyperandrogenism, we performed single-strand conformational polymorphism (SSCP) analysis of the 3beta-hydroxysteroid dehydrogenase type...
Topics
- 17-Hydroxycorticosteroids
- 17-alpha-Hydroxyprogesterone
- 3-Hydroxysteroid Dehydrogenases
- Adolescent
- Adrenal Hyperplasia, Congenital
- Adrenocorticotropic Hormone
- Adult
- Amino Acid Sequence
- Androstenedione
- Breast
- Child
- Female
- Genetic Variation
- Heterozygote
- Hirsutism
- Humans
- Hyperandrogenism
- Male