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Article

Hyperandrogenism and manifesting heterozygotes for 21-hydroxylase deficiency.

Biochemical and molecular medicine - 1 Dec 1997

Witchel S F, Lee P A, Suda-Hartman M, Hoffman E P

Abstract excerpt

Premature adrenarche and functional adolescent androgen excess are common disorders which may evolve into polycystic ovary syndrome (PCOS). In all three disorders, ACTH-stimulated 17-hydroxyprogesterone concentrations are often somewhat elevated. To determine the role of 21-hydroxylase (CYP21) gene mutations in these disorders, we performed molecular genotype analysis on 48 children and adolescents referred for...

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Identifiers

PMID: 9441866
DOI: 10.1006/bmme.1997.2632

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Hyperandrogenism and manifesting heterozygotes for 21-hydroxylase deficiency.PMID 9441866Read ↗

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Hyperandrogenism in carriers of CYP21 mutations: the role of genotype.Semantic proximity Read ↗

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The frequency of CYP 21 gene mutations in Turkish women with hyperandrogenism.Semantic proximity Read ↗

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