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Article

Glucocorticoid resistance in premature pubarche and adolescent hyperandrogenism.

Molecular genetics and metabolism - 1 Feb 1999

Witchel S F, Smith R R

Abstract excerpt

To determine whether glucocorticoid resistance due to mutations in the glucocorticoid receptor (GRL) gene is associated with premature pubarche, hirsutism, or oligo/amenorrhea, we performed single-strand conformational polymorphism analysis of genomic DNA obtained from 25 children and 16 adolescent girls referred for the evaluation of premature pubarche, hirsutism, or oligo/amenorrhea. A missense mutation, N363S,...

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Identifiers

PMID: 10068517
DOI: 10.1006/mgme.1998.2796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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