Article
What is the place of genetics in the pathogenesis of pre-eclampsia?
Biology of the neonate - 1 Dec 1999
Broughton Pipkin F
Abstract excerpt
It is most unlikely that there is a single 'pre-eclampsia (PE) gene'. We are probably looking for a cluster of polymorphisms which, possibly in conjunction with environmental factors, predispose to the development of the condition. Accurate phenotyping is vital for any genetic studies of PE, and since the disease is only clinically-detectable in the second half of pregnancy, is particularly difficult. It is...
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