Article
Genetic analysis of the angiotensinogen gene in pre-eclampsia: study of german women and review of the literature.
Gynecologic and obstetric investigation - 1 Jan 2008
Knyrim Elke, Muetze Sabine, Eggermann Thomas, Rudnik-Schoeneborn Sabine, Lindt Ria, Ortlepp Jan R, Rath Werner, Zerres Klaus
Abstract excerpt
AIMS: To evaluate the influence of the angiotensinogen (AGT) gene on the individual predisposition to pre-eclampsia, we screened the AGT gene for pathogenic mutations and an association of identified polymorphisms in German women with pre-eclampsia. METHODS: The study population consisted of 67 German primi- and multigravid patients with pre-eclampsia or superimposed pre-eclampsia and 100 controls with...
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