Article
Determining the evolutionary potential of a gene.
Molecular biology and evolution - 1 Aug 1998
Hall B G, Malik H S
Abstract excerpt
In addition to information for current functions, the sequence of a gene includes potential information for the evolution of new functions. The wild-type ebgA (evolved beta-galactosidase) gene of Escherichia coli encodes a virtually inactive beta-galactosidase, but that gene has the potential to evolve sufficient activity to replace the lacZ gene for growth on the beta-galactoside sugars lactose and lactulose....
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