Article
A truncated species of apolipoprotein B (B-38.7) in a patient with homozygous hypobetalipoproteinemia associated with diabetes mellitus.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1998
Ohashi K, Ishibashi S, Yamamoto M, Osuga J, Yazaki Y, Yukawa S, Yamada N
Abstract excerpt
Familial hypobetalipoproteinemia is caused by mutations in the apolipoprotein (apo) B gene. We identified a 57-year-old woman whose plasma total cholesterol and apoB levels were 2.17 mmol/L and 0.03 g/L, respectively. Separation of plasma lipoproteins by sodium dodecyl sulfate-polyacrylamide gel...
Topics
- Apolipoproteins B
- Arterial Occlusive Diseases
- Base Sequence
- Calcinosis
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Haplotypes
- Homozygote
- Humans
- Hypobetalipoproteinemias
- Lipoproteins
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Sequence Analysis, DNA