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Article

A truncated species of apolipoprotein B (B67) in a kindred with familial hypobetalipoproteinemia.

The Journal of clinical investigation - 1 May 1991

Welty F K, Hubl S T, Pierotti V R, Young S G

Abstract excerpt

We describe a kindred in which the proband and 6 of his 12 children have hypobetalipoproteinemia. The plasma lipoproteins of the affected subjects contained a unique species of apolipoprotein (apo) B, apo B67, in addition to the normal species, apo B100 and apo B48. The size of apo B67 and immunochemical studies with a panel of apo B-specific antibodies indicated that apo B67 was a truncated species of apo B that...

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Identifiers

PMID: 2022744
DOI: 10.1172/JCI115193
PMCID: PMC295283

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Source receipt: pubmed, retrieved 7 Sept 2026.

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A truncated species of apolipoprotein B (B67) in a kindred with familial hypobetalipoproteinemia.PMID 2022744Read ↗

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A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia.Semantic proximity Read ↗

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Dysbetalipoproteinemia in a kindred with hypobetalipoproteinemia due to mutations in the genes for ApoB (ApoB-70.5) and ApoE (ApoE2).Semantic proximity Read ↗

Donor splice mutation generates a lipid-associated apolipoprotein B-27.6 in a patient with homozygous hypobetalipoproteinemia.Semantic proximity Read ↗

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ApoB-54.8, a truncated apolipoprotein found primarily in VLDL, is associated with a nonsense mutation in the apoB gene and hypobetalipoproteinemia.Semantic proximity Read ↗

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