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Article

Pair-rule gene runt restricts orthodenticle expression to the presumptive head of the Drosophila embryo.

Developmental genetics - 1 Jan 1998

Tsai C C, Kramer S G, Gergen J P

Abstract excerpt

Ectopic expression of the pair-rule gene runt in the anterior end of the Drosophila embryo antagonizes transcriptional activation of the head gap gene orthodenticle (otd) by the anterior morphogen bicoid. Here we investigate the relevance of runt's activity as a repressor of otd in normal Drosoph...

Topics

Animals
Basic Helix-Loop-Helix Transcription Factors
Body Patterning
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Genes, Homeobox
Genes, Insect
Homeodomain Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Proteins

Repressor Proteins

Transcription Factors

Source

Identifiers

PMID: 9706692
DOI: 10.1002/(SICI)1520-6408(1998)23:1<35::AID-DVG4>3.0.CO;2-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9706692-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Pair-rule gene runt restricts orthodenticle expression to the presumptive head of the Drosophila embryo.PMID 9706692Read ↗

The role of eyg Pax gene in the development of the head vertex in Drosophila.Semantic proximity Read ↗

orthodenticle is required for photoreceptor cell development in the Drosophila eye.Semantic proximity Read ↗

Apparent role of Tribolium orthodenticle in anteroposterior blastoderm patterning largely reflects novel functions in dorsoventral axis formation and cell survival.Semantic proximity Read ↗

The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development.Semantic proximity Read ↗

Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors.Semantic proximity Read ↗

Regulation of runt transcription by Drosophila segmentation genes.Semantic proximity Read ↗

Pair-rule expression of the Drosophila fushi tarazu gene: a nuclear receptor response element mediates the opposing regulatory effects of runt and hairy.Semantic proximity Read ↗

Groucho restricts rhomboid expression and couples EGFR activation with R8 selection during Drosophila photoreceptor differentiation.Semantic proximity Read ↗

In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters.Semantic proximity Read ↗

The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures.Semantic proximity Read ↗

Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho.Semantic proximity Read ↗

orthodenticle activity is required for the development of medial structures in the larval and adult epidermis of Drosophila.Semantic proximity Read ↗

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