Article
Clarithromycin-susceptible and -resistant Helicobacter pylori isolates with identical randomly amplified polymorphic DNA-PCR genotypes cultured from single gastric biopsy specimens prior to antibiotic therapy.
Journal of clinical microbiology - 1 Jul 2001
van der Ende A, van Doorn L J, Rooijakkers S, Feller M, Tytgat G N, Dankert J
Abstract excerpt
Of the Helicobacter pylori populations from 976 patients, six contained clarithromycin-resistant as well as -susceptible colonies. In each heterogeneous H. pylori population, resistant H. pylori colonies harbored identical 23S ribosomal DNA (rDNA) mutations associated with clarithromycin resistance, while the susceptible H. pylori colonies all had wild-type 23S rDNA. The resistant and susceptible colonies of each...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.