Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MLL Genomic Breakpoint Distribution Within the Breakpoint Cluster Region in De Novo Leukemia in Children

1 Jul 1998

Abstract excerpt

PURPOSE: To assess translocation breakpoint distribution within the MLL genomic breakpoint cluster region (bcr), 40 cases of de novo leukemia in children were examined by karyotype and Southern blot analysis. PATIENTS AND METHODS: Criteria for inclusion were karyotypic or molecular rearrangement of chromosome band 11q23. Of the 40 cases, 31 occurred in infants. Twenty cases were acute lymphoblastic leukemia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Chronic Myeloid Leukemia Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9703001
DOI: 10.1097/00043426-199807000-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MLL Genomic Breakpoint Distribution Within the Breakpoint Cluster Region in De Novo Leukemia in ChildrenPMID 9703001Read ↗

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sitesSemantic proximity Read ↗

Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patientsSemantic proximity Read ↗

Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal TranslocationsSemantic proximity Read ↗

Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: Almost identical MLL breakpoints in therapy‐related AML after treatment without etoposidesSemantic proximity Read ↗

Genomic<i>BCR</i>‐<i>ABL1</i>breakpoints in pediatric chronic myeloid leukemiaSemantic proximity Read ↗

Identification of CBL, a proto‐oncogene at 11q23.3, as a novel MLL fusion partner in a patient with de novo acute myeloid leukemiaSemantic proximity Read ↗

Chromosomal Aberration of the 11q23 Locus in Acute Leukemia and Frequency of MLL Gene Translocation Results in 378 Adult PatientsSemantic proximity Read ↗

The distribution of <i><scp>MLL</scp></i> breakpoints correlates with outcome in infant acute leukaemiaSemantic proximity Read ↗

Chromosomal Aberration of the 11q23 Locus in Acute Leukemia and Frequency ofMLLGene TranslocationSemantic proximity Read ↗

Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancySemantic proximity Read ↗

Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangementsSemantic proximity Read ↗

Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.