Article
A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 1999
Slee R, Grimes B, Speed R M, Taggart M, Maguire S M, Ross A, McGill N I, Saunders P T, Cooke H J
Abstract excerpt
In a subset of infertile men, a spectrum of spermatogenic defects ranging from a complete absence of germ cells (sertoli cell only) to oligozoospermia is associated with microdeletions of the DAZ (deleted in azoospermia) gene cluster on human distal Yq. DAZ encodes a testis-specific protein with RNA-binding potential recently derived from a single-copy gene DAZL1 (DAZ-like) on chromosome 3. Y chromosomal DAZ...
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