Mutations of androgen receptor gene in Brazilian patients with male pseudohermaphroditism.

doi:10.1590/s0100-879x1998000600008

Article

Mutations of androgen receptor gene in Brazilian patients with male pseudohermaphroditism.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jun 1998

Cabral D F, Maciel-Guerra A T, Hackel C

Abstract excerpt

We describe the identification of point mutations in the androgen receptor gene in five Brazilian patients with female assignment and behavior. The eight exons of the gene were amplified by the polymerase chain reaction (PCR) and analyzed for single-strand conformation polymorphism (SSCP) to dete...

Topics

Adolescent
Adult
Androgen-Insensitivity Syndrome
Brazil
Child, Preschool
Disorders of Sex Development
Female
Humans
Male
Mutation
Point Mutation
Receptors, Androgen

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