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Article

p21 expression is increased by irradiation in esophageal squamous cell carcinoma.

The Journal of surgical research - 1 May 1998

Rigberg D A, Kim F S, Blinman T A, Cole M A, Lane J S, So J, McFadden D W

Abstract excerpt

The p21 cyclin-dependent kinase inhibitor blocks cell cycle transition and replication in response to DNA damage. Although required for p53-mediated cell cycle arrest, p21 expression can also be initiated via p53-independent pathways. This study examines the postirradiation expression of p21 in squamous cell carcinoma (SCC) of the esophagus to determine whether this p21 production is p53-dependent or independent....

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Identifiers

PMID: 9698513
DOI: 10.1006/jsre.1998.5308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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