Article
Molecular, serological and population studies on a novel HLA-B allele--HLA-B*5002.
Tissue antigens - 1 Jun 1998
Darke C, Guttridge M G, Thompson J, Street J, Thomas M
Abstract excerpt
A novel HLA-B allele (B*5002), detected as a discrepancy between serological and PCR-SSP HLA-A and B phenotyping of bone marrow panel donors, was identified by nucleotide sequencing of exons 2 and 3. Titration studies on 39 HLA-B12/B21 cross-reactive antisera showed that the serological specificity of HLA-B*5002 was HLA-B45. PCR-SSP testing of 287 serologically defined HLA-B45-positive subjects from a panel of...
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