Article
A single amino acid exchange shifts the serological reactivity of the novel HLA-B*4442 allele product from HLA-B44 to HLA-B21.
International journal of immunogenetics - 1 Jun 2006
Mrazek F, Fae I, Ambruzova Z, Raida L, Kriegova E, Indrak K, Fischer G F, Petrek M
Abstract excerpt
A novel HLA-B (human leukocyte antigen-B) allele, HLA-B*4442, was identified both in a Czech patient with leukaemia and in his mother. The presence of a novel allele was initially suspected because conflicting results were obtained by serological and DNA typing techniques. The HLA typing using the polymerase chain reaction-sequence-specific primers (PCR-SSP) at the two-digit level indicated an allele belonging to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
