D6S273 microsatellite polymorphism and susceptibility to rheumatoid arthritis.

doi:10.1111/j.1399-0039.1998.tb03055.x

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Article

D6S273 microsatellite polymorphism and susceptibility to rheumatoid arthritis.

Tissue antigens - 1 Oct 1998

Singal D P, Li J, Ye M, Lei K

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic articular inflammatory disease associated with HLA-DR genes that share a five amino acid sequence motif, QKRAA or QRRAA, from position 70 to 74 in the third hypervariable region of the DRB1 molecule. Since these associations between DRB1 genes and susceptibi...

Topics

Adult
Alleles
Arthritis, Rheumatoid
Genetic Predisposition to Disease
HLA-DR Antigens
Humans
Microsatellite Repeats
Polymorphism, Genetic

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