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Article

The role of histidine residues in the HXGH site of CTP:phosphocholine cytidylyltransferase in CTP binding and catalysis.

European journal of biochemistry - 1 Jul 1998

Veitch D P, Gilham D, Cornell R B

Abstract excerpt

The HXGH motif of CTP:phosphocholine cytidylyltransferase (CCT) is a unifying feature of the cytidylyltransferase family which has been proposed to function in binding of CTP and catalysis [Veitch, D. P. & Cornell, R. B. (1996) Biochemistry 35, 10743-10750]. Substitution of serine for Gly91 in the HXGH motif of CCT implicates this motif in CTP-binding [Park, Y. S., Gee, P., Sanker, S., Schuster, E. J., Zuiderweg,...

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Identifiers

PMID: 9692923
DOI: 10.1046/j.1432-1327.1998.2550227.x

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