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High‐mobility group protein 1(Y): Metastasis‐associated or metastasis‐inducing?

21 Oct 2004

Abstract excerpt

Metastasis is the major cause of mortality and morbidity for patients with cancer. The high-mobility group protein 1(Y) [HMG-1(Y)] has a role in the transcription of many genes involved at different steps in the metastatic cascade and has been linked with cancer in human and animal models. This may represent a potential therapeutic target for patients. The following review summarizes and critically appraises the...

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PMID: 15499602
DOI: 10.1002/jso.20136

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