Article
Hyperlipidaemia associated with genetic variation in the apolipoprotein B gene.
Current opinion in lipidology - 1 Aug 1995
Humphries S E, Talmud P J
Abstract excerpt
Common variants at the apolipoprotein B gene locus are associated with hyperlipidaemia, but conflicting data have been presented in the literature concerning the size of the effects and which polymorphisms give the best signal in the different groups of individuals studied. In this review, we will present a critique on the use and interpretation of association studies, with respect to the recent apolipoprotein B...
Topics
- Amino Acid Sequence
- Apolipoprotein B-100
- Apolipoproteins B
- Environment
- Humans
- Hyperlipidemias
- Linkage Disequilibrium
- Molecular Sequence Data
- Mutation
- Polymorphism, Restriction Fragment Length
- Protein Sorting Signals