Article
[WR, a new strain of mice, highly sensitive to the cytogenetic effect of thiotepa].
TSitologiia i genetika - 1 Jan 2000
Malashenko A M, Surkova N I
Abstract excerpt
Mice of the WR strain (genotype -aa, +WY) were selected for the appearance of black spots with normal pigmentation, presumably due to genetic recombination in the W gene region. The frequency of heterozigotes +WY with black spots was 25% in the 11th generation. The cytogenetic effect of thioTEPA (dose 5 mg/kg) was investigated in bone marrow cells of C57BL/10 NZW, 101/H and 129/Re mice. Mice of the WR strain were...
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