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Article

[WR, a new strain of mice, highly sensitive to the cytogenetic effect of thiotepa].

TSitologiia i genetika - 1 Jan 2000

Malashenko A M, Surkova N I

Abstract excerpt

Mice of the WR strain (genotype -aa, +WY) were selected for the appearance of black spots with normal pigmentation, presumably due to genetic recombination in the W gene region. The frequency of heterozigotes +WY with black spots was 25% in the 11th generation. The cytogenetic effect of thioTEPA...

Topics

Animals
Bone Marrow
Chromosome Aberrations
Crosses, Genetic
Female
Heterozygote
Male
Mice
Mice, Inbred C57BL
Mice, Inbred NZB
Mice, Inbred Strains
Mosaicism
Mutation

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Thiotepa

Source

Identifiers

PMID: 117576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-117576-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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