Article
Polymorphism in tumor necrosis factor genes associated with myasthenia gravis.
Journal of neuroimmunology - 1 Aug 1998
Hjelmström P, Peacock C S, Giscombe R, Pirskanen R, Lefvert A K, Blackwell J M, Sanjeevi C B
Abstract excerpt
The aim of this study was to analyze associations between myasthenia gravis (MG) and polymorphisms in the tumor necrosis factor (TNF) region in 79 Swedish patients and 155 unrelated controls. The frequency of the TNFa2 allele of a microsatellite located 3.5 kb upstream of the lymphotoxin alpha (L...
Topics
- Age of Onset
- Alleles
- Humans
- Introns
- Lymphotoxin-alpha
- Microsatellite Repeats
- Myasthenia Gravis
- Peptide Fragments
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Reference Values
- Tumor Necrosis Factor-alpha