Article
Tumor necrosis factor-alpha polymorphism and secretion in myasthenia gravis.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Jun 2005
Guan Yu-zhou, Cui Li-ying, Li Yan-feng, Zhang Jun-bao
Abstract excerpt
OBJECTIVE: To analyze the relationship between tumor necrosis factor-alpha (TNFalpha) gene promoter -308 polymorphism and myasthenia gravis (MG) in Chinese and analyze secretion of TNFalpha in peripheral blood mononuclear cells (PBMC) in MG patients. METHODS: A biallelic polymorphism at position -308 in the promoter of TNFalpha gene was screened by PCR amplification and NcoI recognition site. One hundred and...
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