Article
Pleiotropic phenotype of acetyl-CoA-carboxylase-defective yeast cells--viability of a BPL1-amber mutation depending on its readthrough by normal tRNA(Gln)(CAG).
European journal of biochemistry - 15 Jun 1998
Hoja U, Wellein C, Greiner E, Schweizer E
Abstract excerpt
The Saccharomyces cerevisiae gene BPL1 encodes the enzyme biotin:protein ligase (BPL), which is required for acetyl-CoA carboxylase (ACC) holoenzyme formation. Disruption of one of the two BPL1 alleles present in diploid cells results, upon sporulation, in a 2+:2(0) segregation of cell viability,...
Topics
- Acetyl-CoA Carboxylase
- Bacterial Proteins
- Base Sequence
- Carbon-Nitrogen Ligases
- DNA Primers
- Escherichia coli Proteins
- Genetic Complementation Test
- Phenotype
- Point Mutation
- RNA, Transfer, Gln
- Repressor Proteins
- Saccharomyces cerevisiae
- Transcription Factors