HLA-DQA1 and HLA-DQB1 alleles and haplotypes in two Brazilian Indian tribes: evidence of conservative evolution of HLA-DQ.

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Article

HLA-DQA1 and HLA-DQB1 alleles and haplotypes in two Brazilian Indian tribes: evidence of conservative evolution of HLA-DQ.

Human biology - 1 Aug 1998

Sotomaior V S, Faucz F R, Schafhauser C, Janzen-Dück M, Boldt A B, Petzl-Erler M L

Abstract excerpt

Nucleotide sequence polymorphism of the HLA-DQA1 and HLA-DQB1 class II genes was analyzed in the Kaingang and Guarani Amerindians from southern Brazil using PCR sequence-specific oligonucleotide typing methods. Four different DQA1-DQB1 haplotypes were found: DQA1*0401-DQB1*0402 (associated with D...

Topics

Alleles
Biological Evolution
Brazil
Gene Frequency
Genetic Variation
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
Haplotypes
Humans
Indians, South American
Polymorphism, Genetic
Selection, Genetic

Source

Open in PubMed

Identifiers

PMID: 9686487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9686487-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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