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Article

Accumulation of genetic alterations and their significance in each primary human cancer and cell line.

Mutation research - 25 May 1998

Murakami Y, Sekiya T

Abstract excerpt

Analyses of multiple genetic alterations accumulated in each cancer cell is expected to provide useful information to elucidate the molecular mechanisms involved in tumorigenesis. Here, we summarized the results of studies on aberrations of oncogenes and tumor suppressor genes by ourselves and other groups. DNAs analyzed were from particular sets of surgical specimens from human tumors and cancer cell lines...

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Source

Identifiers

PMID: 9685701
DOI: 10.1016/s0027-5107(98)00031-1

Genes

CDK4
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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