Accumulation of genetic alterations and their significance in each primary human cancer and cell line.

doi:10.1016/s0027-5107(98)00031-1

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Article

Accumulation of genetic alterations and their significance in each primary human cancer and cell line.

Mutation research - 25 May 1998

Murakami Y, Sekiya T

Abstract excerpt

Analyses of multiple genetic alterations accumulated in each cancer cell is expected to provide useful information to elucidate the molecular mechanisms involved in tumorigenesis. Here, we summarized the results of studies on aberrations of oncogenes and tumor suppressor genes by ourselves and ot...

Topics

Cell Division
DNA Mutational Analysis
Humans
Mutation
Neoplasms
Polymorphism, Single-Stranded Conformational
Tumor Cells, Cultured

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