Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of genomic DNA alterations and mRNA expression patterns in a panel of human pancreatic cancer cell lines

31 May 2005

Abstract excerpt

Genomic alterations influencing the expression and/or activity of tumor suppressors or oncogenes such as KRAS2, CDKN2A, TP53, and DPC4 have been directly implicated in the initiation and progression of human pancreatic adenocarcinoma. In an effort further to systematically characterize the genomic alterations that occur in this disease, we conducted a genome wide analysis of alterations in gene copy number using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genomic variations and chromosomal abnormalities
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15929091
DOI: 10.1002/gcc.20216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of genomic DNA alterations and mRNA expression patterns in a panel of human pancreatic cancer cell linesPMID 15929091Read ↗

Pancreatic adenocarcinoma—Genetic portrait from chromosomes to microarraysSemantic proximity Read ↗

Genomic alterations in pancreatic cancer and their relevance to therapySemantic proximity Read ↗

High-resolution characterization of the pancreatic adenocarcinoma genomeSemantic proximity Read ↗

Array-Based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic CancerSemantic proximity Read ↗

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.Semantic proximity Read ↗

High-Resolution Genomic and Expression Profiling Reveals 105 Putative Amplification Target Genes in Pancreatic CancerSemantic proximity Read ↗

Genome-Wide Array-Based Comparative Genomic Hybridization Reveals Multiple Amplification Targets and Novel Homozygous Deletions in Pancreatic Carcinoma Cell LinesSemantic proximity Read ↗

Genome‐wide array‐based comparative genomic hybridization analysis of pancreatic adenocarcinoma: Identification of genetic indicators that predict patient outcomeSemantic proximity Read ↗

DNA microarray analysis of pancreatic malignanciesSemantic proximity Read ↗

Characterization of the 7q21‐q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancerSemantic proximity Read ↗

Expression analysis of pancreatic cancer cell lines reveals association of enhanced gene transcription and genomic amplifications at the 8q22.1 and 8q24.22 loci.Semantic proximity Read ↗

Identification of genomic alterations associated with the aggressiveness of pancreatic cancer using an ultra-high-resolution CGH array.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.