Article
p53 intron 2 genotypes detected in normal specimens and lung carcinomas in Hong Kong.
Oncology reports - 1 Jan 2000
Ge H, Wong M P, Lam W K, Lee J, Fu K H, Yew W W, Lung M L
Abstract excerpt
Previous studies suggest that the polymorphic p53 intron 2 displays a high frequency of mutations, occurring with different frequencies in tumor tissues versus peripheral blood of lung cancer patients as compared to healthy individuals. We evaluated the significance of these polymorphisms and mutations utilizing matched triple specimens from the lung tumor, normal lung tissue, and peripheral blood of cancer...
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