Article
p53 intron 2 genotypes detected in normal specimens and lung carcinomas in Hong Kong.
Oncology reports - 1 Jan 2000
Ge H, Wong M P, Lam W K, Lee J, Fu K H, Yew W W, Lung M L
Abstract excerpt
Previous studies suggest that the polymorphic p53 intron 2 displays a high frequency of mutations, occurring with different frequencies in tumor tissues versus peripheral blood of lung cancer patients as compared to healthy individuals. We evaluated the significance of these polymorphisms and mut...
Topics
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Female
- Genes, p53
- Genotype
- Hong Kong
- Humans
- Introns
- Lung
- Lung Neoplasms
- Male
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Reference Values
- Retrospective Studies